In 2017, a team of researchers led by Shoukhrat Mitalipov, a geneticist at Oregon Health and Science University in Portland, reported that human embryos carrying a mutation could be coaxed into this process without a synthetic template. The researchers generated embryos from a union between two cells: a sperm carrying a mutation that can make it harder for the heart to pump blood, and an egg with a healthy version of the gene. Dr. Mitalipov and his team used Crispr-Cas9 to cut the broken copy of the gene to see if the intact version would guide its repair. They reported the experiment a success and published it in the journal Nature.
“In principle, this could be a way to correct a mutation in a human embryo” that has only one broken copy of a gene, Dr. Egli said.
But the new findings could cast some doubt on the 2017 work, Dr. Egli added.
The researchers of the Cell study focused on a different mutation — one that causes hereditary blindness and affects a different part of the genome — but adopted a similar setup. Using donated sperm containing a mutation in a gene called EYS, they fertilized eggs that
The Centers for Disease Control and Prevention on Friday lifted its “no sail” order on U.S. cruise ships and set out a framework for how cruising could restart.Under the new...
As a veteran television journalist, Sally-Ann Roberts knows how to tame an unsteady landscape and will it into submission. She survived 40 years reporting and anchoring the news for WWL-TV...
In addition to his wife, Christine (Martin) Pendergast, a past president of the Port Jefferson Station Teachers Association on Long Island, he is survived by a son, Christopher, who is...
Join us for a great discussion that sheds new light on how we should be treating mental health issues. Guest information for ‘Barry L. Duncan- Therapist or Patient’ Podcast...
Long-term exposure to noise may be linked to an increased risk for Alzheimer’s disease and other forms of dementia.Researchers did periodic interviews with 5,227 people 65 and older participating in...
The 61-year-old woman put on her reading glasses to try to decipher the tiny black squiggles on the back of the package of instant pudding. Was it two cups of...
By talking openly about her family’s four suicides, mental illness, substance abuse, family affairs, and more, Rachel is changing the narrative and replacing it with love, compassion, and understanding. (Transcript...
This obituary is part of a series about people who have died in the coronavirus pandemic. Read about others here.Jeannette Williams-Parker loved rock music from the 1980s and ’90s. She...
Here is a sampling of the week’s events and how to tune in (all times are Eastern). Note that events are subject to change after publication.MondaySee the novelist Marlon James...